Skip to Content

How long does KISQALI extend life?

Kisqali is a medication that is used to treat breast cancer in postmenopausal women. It is an oral medication that targets certain proteins in cancer cells and stops the growth and spread of cancerous cells. The use of Kisqali in conjunction with other medications has been shown to increase the overall survival rate and prolong the progression-free survival of patients with advanced breast cancer.

However, the question of how long Kisqali extends life is not very straightforward. The effectiveness of the drug varies from patient to patient, and it depends on many factors such as the stage of cancer, age, overall health, and other medical conditions of the patient. According to clinical trials, the addition of Kisqali to other medications has shown an improvement in progression-free survival in patients with advanced or metastatic breast cancer.

In one clinical trial (MONALEESA-7) involving younger women with advanced breast cancer, the use of Kisqali, along with other medications (aromatase inhibitors), substantially increased the overall survival rate by 10 months, compared to those who did not receive the drug regimen. In another clinical trial (MONALEESA-3) of postmenopausal women with advanced breast cancer, Kisqali in combination with fulvestrant, extended progression-free survival by more than eight months.

So, the use of Kisqali has shown promising improvements in the overall survival rate of advanced breast cancer patients, but the drug’s extension of life varies greatly from patient to patient. It is important to note that the medication has potential side effects, and the use of the medication should be discussed with healthcare professionals to determine if it is appropriate and safe for the patient’s specific condition.

Additionally, it is vital that patients continue with routine cancer screening and monitoring while receiving treatment with Kisqali. Healthcare professionals can best guide patients and their families regarding the benefits and risks of using Kisqali as a viable treatment option.

How long does ribociclib work for?

Ribociclib is a medication that belongs to a class of drugs called CDK4/6 inhibitors, which are used to treat advanced breast cancer. These drugs work by blocking the activity of CDK4 and CDK6 enzymes, which play a key role in cancer cell growth and division.

The duration of action of ribociclib can vary from person to person, depending on various factors such as the stage and type of cancer being treated, the individual’s overall health, and the treatment plan recommended by the healthcare provider.

In clinical trials, ribociclib has been shown to provide significant benefits in terms of progression-free survival (PFS), which is the length of time during which the cancer does not worsen. According to data from clinical studies, ribociclib has an average PFS of around 25-28 months when used in combination with other therapies such as hormone therapy.

However, it is important to note that ribociclib is not a cure for cancer and the benefits of treatment may vary depending on individual circumstances. The medication is typically given in cycles, with breaks in between to allow the body to recover from any potential side effects. The duration of treatment can vary depending on how well the patient is tolerating the medication and how effective it is in controlling the growth of cancer cells.

The efficacy and duration of ribociclib treatment depend on several factors, including the stage and type of cancer being treated, the patient’s overall health, and the specific treatment plan recommended by the healthcare provider. Patients should work closely with their healthcare team to determine the best course of treatment and the appropriate duration of ribociclib treatment for their individual circumstances.

What does KISQALI do to your body?

KISQALI (ribociclib) is a medication used for the treatment of advanced breast cancer, specifically hormone receptor-positive and HER2-negative breast cancer. KISQALI works by inhibiting a group of proteins called cyclin-dependent kinases (CDKs) that are involved in cell division and growth.

In breast cancer, CDKs are overactive, leading to uncontrolled cell growth and division. By inhibiting CDKs, KISQALI can slow down or stop the growth and spread of cancer cells. This medication is often used in combination with other cancer treatments, such as hormonal therapies.

KISQALI is administered orally in the form of a tablet and is typically taken once daily for 21 consecutive days, followed by a 7-day break. The dosage and duration of treatment may vary depending on individual patient factors and response to the medication.

While KISQALI is effective in treating breast cancer, it also has potential side effects. Common side effects of KISQALI include low white blood cell count, fatigue, nausea, vomiting, diarrhea, and hair loss. Patients taking KISQALI should also have their heart function regularly monitored, as the medication can cause QT prolongation, a condition that can lead to abnormal heart rhythms.

It is important to follow the treatment plan and regularly communicate with your healthcare team while taking KISQALI. Patients should report any side effects they experience and follow any precautionary measures recommended by their healthcare provider to ensure the safe and effective use of the medication.

How long can you live with stage 4 breast cancer?

The prognosis for an individual diagnosed with stage 4 breast cancer can vary and depends on several factors like age, overall health, specific type of breast cancer, and response to treatment. As stage 4 breast cancer is considered an advanced stage of the disease, it means that the cancer cells have spread beyond the breast to other parts of the body.

This makes it very challenging to treat and manage.

While it is impossible to predict how long someone with stage 4 breast cancer can live, some statistics show that the five-year survival rate ranges from 22% to 36%, depending on various factors. Some individuals may respond well to treatment and live longer, while others may not respond well to therapy and have a shorter life expectancy.

Treatment for stage 4 breast cancer usually involves a combination of surgery, radiation therapy, chemotherapy, targeted therapy, and hormone therapy. Though treatment may not cure the cancer, it can help to slow down its progression and alleviate symptoms, improving the quality of life for some individuals.

Apart from medical treatment, emotional support and a holistic approach to health can also play a significant role in prolonging the life of an individual with stage 4 breast cancer. Lifestyle changes such as a healthy diet, regular exercise, and stress management can help to improve overall health and well-being.

It’s important to remember that every person’s journey with cancer is unique, and each individual’s prognosis and life expectancy can vary. It’s possible to live for several years with stage 4 breast cancer, but it’s also important to prepare for the worst while hoping for the best. Medical professionals can provide more specific information and support for those affected by stage 4 breast cancer.

Can you live 20 years with metastatic breast cancer?

There is no clear-cut answer to this question as the survival rate for metastatic breast cancer varies from person to person. However, thanks to advancements in cancer treatment and technology, many individuals have been able to live long, meaningful lives even while dealing with metastatic breast cancer.

Metastatic breast cancer is when cancer cells from the breast spread to other parts of the body, such as the bones, liver or lungs. This condition can be challenging to treat since the cancer has already spread beyond the breast tissue. It is typically treated with a combination of chemotherapy, targeted therapy, hormone therapy and surgery.

According to the American Cancer Society, the five-year survival rate for people diagnosed with metastatic breast cancer is around 22%. This means that, on average, approximately 22% of these individuals will live for at least five years after their diagnosis. However, this statistic does not take into account individual factors such as age, overall health, the extent and location of the metastasis, and response to treatment.

Some individuals have been able to live for longer than five years with metastatic breast cancer. They have been successful in managing their condition through a combination of medical treatments, lifestyle changes, and emotional support. There are also cases where individuals have been able to achieve remission or stable disease, where their cancer is not active or growing.

While living with metastatic breast cancer can be challenging, it is important to remember that it is possible to lead a full and meaningful life. With the right support, an individual can continue to work, travel, pursue their hobbies, and spend time with loved ones.

While there is no definitive answer to how long someone can live with metastatic breast cancer, it is clear that survival rates have improved, and many individuals are able to live with this condition for many years. It is essential that those living with metastatic breast cancer have access to the resources and support they need to manage their condition and maintain a high quality of life.

What are the final stages of stage 4 breast cancer?

Breast cancer is a malignant tumor that develops in the cells of the breast tissue. It is a progressive disease that advances through several stages as it grows and spreads from its point of origin. The final stages of stage 4 breast cancer, which is also known as metastatic breast cancer, are characterized by severe symptoms that can significantly affect a patient’s quality of life.

Stage 4 breast cancer is the most advanced stage of breast cancer. At this stage, the cancer has spread beyond the breast and nearby lymph nodes to other parts of the body, such as the bones, lungs, liver or brain. The final stages of stage 4 breast cancer are typically defined by the spread and growth of cancer to other areas of the body, often leading to the failure of multiple organs.

The primary symptoms of the final stages of stage 4 breast cancer may include extreme fatigue, pain, weight loss, and loss of appetite. As the cancer spreads to other organs, patients may also experience organ-specific symptoms such as breathing difficulty, jaundice, nausea, and confusion. Physical distress, mood changes, and discomfort are common in patients during these stages.

Additionally, many patients may also experience emotional and psychological distress, which can include anxiety, depression, and a sense of despair. Moreover, loved ones and caregivers also face significant emotional strain during this period, as they witness the physical and emotional toll the cancer is taking on their loved ones.

Despite advances in cancer treatments, there is currently no cure for stage 4 breast cancer. However, various therapies can help to manage symptoms and prolong the patient’s life, including hormone therapy, chemotherapy, targeted therapy, immunotherapy, and radiation therapy. Palliative care may also be implemented to improve the quality of life of the patient by managing symptoms, and improving communication with loved ones.

The final stages of stage 4 breast cancer are characterized by severe symptoms and emotional strain that impact the patient and their loved ones. Yet, support from caregivers, palliative care, and exploring the necessary medical interventions can make the journey of a patient manageable and improve the quality of life.

Early detection and treatment of breast cancer have proven to be vital, and hence, it is essential to be aware of the signs and carry out breast cancer screening as recommended by health professionals.

Is there hope for Stage 4 breast cancer?

Breast cancer is a deadly disease that has become a leading cause of death among women worldwide. Stage 4 breast cancer, also known as metastatic breast cancer, is a diagnosis where the cancer has spread beyond the breast and lymph nodes to other parts of the body like the liver, lungs, or brain. This stage is considered the most advanced stage of breast cancer, and the chances of survival become significantly low.

However, it is still not the end of the road as there are various treatments available that can help prolong the life of the patient and improve their quality of life. The treatment approach for this stage of breast cancer is not a one-size-fits-all as the treatment plan is tailored to the individual needs of the patient.

Some of the treatments for stage 4 breast cancer include chemotherapy, radiation therapy, hormone therapy, surgery, and targeted therapy. These treatments can help control the cancer spread and manage the symptoms, improving the patient’s quality of life. Moreover, clinical trials are constantly being conducted to develop new treatments and improve the existing ones.

The prognosis for stage 4 breast cancer varies widely depending on various factors such as the age and overall health of the patient, the hormone receptor status of the cancer, the location and number of metastases, and the response to treatment. Although Stage 4 breast cancer is not curable, there is still hope for improving the patient’s prognosis and prolonging their life.

Stage 4 breast cancer is a severe diagnosis; however, there are still various treatments available to manage symptoms and control the spread of the cancer. With scientific research, innovative treatment approaches, and the support of family and friends, there is still hope for Stage 4 breast cancer patients to live a fulfilling life.

It is vital to stay positive, maintain a healthy lifestyle, and adhere to the treatment plan to improve the patient’s prognosis.

Is Stage 4 breast cancer the last stage?

Stage 4 breast cancer, also known as metastatic breast cancer, is considered the most advanced stage of breast cancer. At this stage, cancer cells have spread from the breast to other parts of the body through the bloodstream or lymphatic system. This means that cancer cells may have invaded vital organs such as the bones, liver, or lungs, making it more difficult to treat.

While stage 4 breast cancer is the most advanced stage, it’s important to note that survival rates and treatment options vary depending on several factors. For example, the subtype of breast cancer, the age and overall health of the patient, and the extent of metastasis all have a significant impact on a patient’s prognosis.

Treatment for stage 4 breast cancer typically includes a combination of systemic therapies, such as chemotherapy, hormone therapy, and targeted therapy. These treatments aim to slow the growth and spread of cancer cells, relieve symptoms, and improve quality of life. In some cases, surgery or radiation therapy may be recommended to treat specific tumors or relieve pain.

Despite treatment, stage 4 breast cancer cannot be cured. However, with advancements in treatment and improved awareness, many women are living longer with metastatic breast cancer. Survival rates for stage 4 breast cancer vary greatly and are influenced by several factors. Some patients may live for many years with the disease, while others may experience a more aggressive form of cancer with a shorter life expectancy.

While stage 4 breast cancer may be the last stage of breast cancer, it’s important to remember that every person’s journey with cancer is unique. With early detection, effective treatment, and ongoing support, many women with breast cancer, including stage 4, are able to live full and meaningful lives.

So, it is crucial to develop awareness about breast cancer and its stages and also to undergo regular screenings and seek medical attention if any symptoms of breast cancer are observed.

Does Medicare Part D cover KISQALI?

Medicare Part D is a prescription drug coverage plan that provides coverage for a wide range of prescription drugs, including oncology drugs, which are used to treat cancer. KISQALI, also known as ribociclib, is a prescription medication used for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer in women who have gone through menopause.

Whether or not Medicare Part D covers KISQALI depends on various factors, such as the specific Part D plan chosen by the beneficiary, the dosage prescribed by the prescribing physician, and the formulary of the plan selected. The formulary of a Medicare Part D plan is a list of covered drugs that outlines the drugs that the plan covers, specific exclusions or limitations, and any applicable cost-sharing amounts.

If a specific Medicare Part D plan covers KISQALI, then the beneficiary will have access to the medication and will be responsible for the applicable cost-sharing amounts, such as copayments, coinsurance, or deductibles. However, if the plan does not cover KISQALI or only covers it with limitations or exclusions, then the beneficiary may need to consider alternative medication options or coverage options.

It is important to note that Medicare Part D plans can change their formularies throughout the year, and beneficiaries should review their plan information regularly to ensure that the drugs they need are covered. Additionally, beneficiaries can discuss their medication options with their prescribing physician and their Medicare Part D plan provider to determine the most cost-effective and appropriate medication option for their specific needs.

What drugs are excluded from Part D plans?

Part D plans, also known as prescription drug plans, are an essential component of the Medicare program. They offer seniors and individuals with disabilities access to affordable prescription drugs. However, there are some drugs that are excluded from Part D plans, leaving enrollees to pay out-of-pocket.

Generally, drugs that are excluded from Part D plans fall into three categories:

1. Drugs not approved by the FDA: The Food and Drug Administration (FDA) is responsible for approving all prescription drugs sold in the United States. Medicare only covers drugs that have been approved by the FDA, which means that drugs that have not yet been approved are excluded from Part D plans.

2. Drugs that are not medically necessary: Medications that are not deemed medically necessary are also excluded from Part D plans. This includes drugs used for cosmetic purposes, as well as those used for weight loss or hair growth.

3. Drugs that are covered under Medicare Part A or Part B: Certain drugs that are covered under Medicare Part A or Part B are excluded from Part D plans. This includes drugs administered in a hospital or doctor’s office, as well as vaccines.

Additionally, Part D plans are not required to cover drugs that are considered to be “excluded” or “restricted” by Medicare. For example, drugs used for weight loss, fertility, and erectile dysfunction are generally excluded from coverage under Medicare.

It’s important to note that even if a drug is excluded from Part D plans, it may still be covered under a Medicare Advantage plan. Medicare Advantage plans are offered by private insurance companies and can provide additional benefits beyond what is offered through traditional Medicare. When choosing a Medicare Advantage plan, it’s important to check the plan’s formulary to see if the medications you need are covered.

Drugs that are not approved by the FDA, not medically necessary, or already covered under Medicare Part A or Part B are typically excluded from Part D plans. However, it’s always important to review the formulary of your specific plan to determine what medications are covered and which are not.

What is the monthly cost of KISQALI?

KISQALI is a medication used in the treatment of advanced breast cancer in postmenopausal women. The cost of KISQALI can vary depending on several factors such as location, insurance coverage, dosage, and duration of treatment. Typically, the monthly cost of KISQALI without any insurance or financial assistance programs can range from $10,000 to $14,000 in the United States.

Many insurance companies do cover KISQALI under their plans, but the actual cost can still depend on the specific coverage and copay requirements. There are also various financial assistance programs available to help patients cover the cost of KISQALI. Some of these programs include patient assistance programs sponsored by the manufacturer, nonprofit organizations, and government programs such as Medicaid.

It is important for patients to discuss the cost of KISQALI with their healthcare providers and insurance companies to determine the best options available to them for covering the cost of treatment. Your healthcare provider can provide you with information about financial assistance programs available to help you afford the medication if you have trouble paying for it.

They can also provide you with resources to help you navigate the healthcare system and get the most out of your insurance benefits.

Do Medicare Part D plans cover chemotherapy drugs?

Yes, Medicare Part D plans do cover chemotherapy drugs. The Medicare Part D prescription drug benefit provides coverage for prescription drugs, including those used in the treatment of cancer. Chemotherapy drugs are covered under Part D plans as long as they are prescribed by a doctor and approved by the Food and Drug Administration (FDA) for use in the treatment of cancer.

It should be noted that coverage for chemotherapy drugs may vary depending on the specific Part D plan chosen. Different plans may have different formularies, or lists of covered drugs, and some may have different levels of cost sharing, such as copayments or deductibles. It is important for beneficiaries to carefully review the formulary and cost sharing for each Part D plan in order to choose a plan that meets their individual needs and preferences.

Additionally, some chemotherapy drugs may be covered by a patient’s Medicare Part B plan, which covers outpatient medical services, including some types of chemotherapy administered in a clinic or doctor’s office. Part B coverage for chemotherapy may be subject to deductibles, coinsurance, and other cost sharing.

Medicare Part D plans do cover chemotherapy drugs, but coverage may vary depending on the specific plan chosen. It is important for beneficiaries to carefully review the plans available to them and their associated formularies and cost sharing in order to choose a plan that best meets their individual healthcare needs.

Which of the following medication does Medicare Part D not cover?

Medicare Part D is a government program designed to help senior citizens and other eligible individuals afford vital prescription drug coverage. Medicare Part D offers prescription drug benefits through private insurance companies that are approved by Medicare. However, not all medications are covered by Medicare Part D.

In general, the medications that are not covered by Medicare Part D are those that are not approved by the United States Food and Drug Administration (FDA), or those that are primarily used for cosmetic purposes. For example, Medicare Part D does not cover over-the-counter medications, such as aspirin or ibuprofen, because they can be purchased without a prescription.

Additionally, some medications are not covered by Medicare Part D because they are considered to be too expensive or too dangerous. These can include drugs that have not been proven to be effective, or that have a high risk of side effects or complications. More specifically, some chemotherapy and other cancer treatments are not covered by Medicare Part D because of their high cost.

Other medications that are not covered by Medicare Part D include those that are used for weight loss, hair growth, or fertility. These medications are typically considered to be cosmetic and are not deemed to be medically necessary.

While the vast majority of outpatient prescription drugs are covered by Medicare Part D, there are some medications that are not covered. It is important for beneficiaries to understand what is and is not covered by their Medicare Part D plan, and to work with their doctors and pharmacists to find affordable alternatives if necessary.

Does Part D have to cover all medications?

Part D of the Medicare program is designed to provide prescription drug coverage to eligible beneficiaries. While Part D coverage is expansive and covers a wide range of prescription drugs, there are certain drugs and medications that are not covered. Therefore, Part D does not have to cover all medications.

One of the reasons why Part D doesn’t have to cover all medications is that Part D coverage is offered by private insurance companies that are contracted by Medicare. The private insurers are required to offer a standard set of benefits as outlined by Medicare, but they have the flexibility to customize their plans to suit their needs.

The private insurers must offer at least two prescription drug plans with different levels of coverage but have a range of flexibility in the drugs and medications they cover.

In addition, Medicare requires the insurers to cover drugs that are medically necessary for the treatment of a specific illness. Certain drugs may not be covered if there are alternative drugs that are equally effective and less costly. This means that the insurers may require prior authorization for some drugs, or they may have step-therapy requirements that require beneficiaries to try lower-cost drugs before being allowed to use a more expensive one.

Some other drugs that might not be covered under Part D include those that are not FDA approved, cosmetic drugs that aren’t needed for medical reasons, and drugs that are not prescribed by a Medicare-approved provider. In addition, some drugs may have coverage rules that limit coverage to a specific quantity, duration or frequency.

Part D does not have to cover all medications. The private insurers contracted by Medicare can tailor their prescription drug plans to suit their own needs while still meeting the minimum requirements set by Medicare. Medicare requires the insurers to cover medically necessary drugs but allows them to set rules and restrictions for coverage based on each drug’s safety and effectiveness characteristics.

Are OTC drugs covered by Part D?

The short answer to the question is that it depends. OTC or Over-the-Counter drugs are medications that can be purchased without a prescription from a healthcare provider. These drugs are generally used for treating minor health conditions such as headaches, colds, allergies, and other common ailments.

Part D is a prescription drug coverage plan offered by Medicare that covers the cost of prescription drugs.

Medicare Part D coverage includes a list of prescription drugs that are approved by the Medicare program. These drugs are identified as “part D drugs” and are the only drugs that are covered by the plan. OTC drugs, on the other hand, are not typically included in the list of part D drugs. Thus, OTC drugs are not generally covered by Part D unless they are prescribed by a doctor or healthcare provider, and are considered as medically necessary.

It is worth noting that there are certain OTC drugs that have prescription-strength formulations that require a prescription from a healthcare provider. In such cases, these OTC drugs are covered by Part D as prescription medication. Such drugs include nicotine replacement products to help quit smoking, prenatal vitamins with a prescription, and some types of insulin which are now available without a prescription but require a doctor’s prescription to be fully covered by Part D. Furthermore, some Medicare Advantage Prescription Drug (MAPD) plans may cover some OTC drugs as part of their drug coverage.

While OTC drugs are not generally covered by Medicare Part D, there may be exceptions depending on the specific drug and the individual’s circumstances. It is always advisable to check with your healthcare provider or the Part D plan provider to know if your OTC medications are covered or if you may require a prescription for them to be covered.

Resources

  1. Kisqali increases overall survival in advanced breast cancer …
  2. Novartis’ Kisqali Adds Years to Breast Cancer Patients’ Lives
  3. Treatment Combination Breaks the ‘5-Year Ceiling’ in …
  4. Ribociclib Improves Survival in Advanced Breast Cancer – NCI
  5. Kisqali Improves Survival in Premenopausal ER+ Advanced …