Multiple myeloma is a form of cancer that develops in the plasma cells of the bone marrow. It primarily affects adults over the age of 65, with the average age being 70 and cases rarely occurring in those under the age of 40.
It is also more common in African Americans and people of African lineage. People who have first-degree relatives (parents, siblings or children) with multiple myeloma tend to have an increased risk of developing the condition.
Other known risk factors include a diet with high amounts of saturated fats, an occupational history of exposure to certain chemicals, and certain genetic disorders such as Monoclonal Gammopathy of Undefined Significance (MGUS).
People exposed to high levels of radiation to the area around the spine, due to certain medical treatments and procedures such as radiation therapy for other cancers, may be at increased risk for developing multiple myeloma.
So it is important to focus on preventive measures such as a healthy lifestyle.
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Who is most at risk for multiple myeloma?
Multiple myeloma is a type of cancer sometimes referred to as plasma cell myeloma, which affects white blood cells in the bone marrow. It is most often found in middle-aged and older adults and is more likely to occur in people with a family history of the disease.
People of African descent and those with chronic immunological conditions, such as HIV, have an increased risk of developing multiple myeloma. Additionally, African Americans are three times more likely to be diagnosed with the condition than other ethnic groups.
Risk factors for developing multiple myeloma include genetic predisposition, radiation exposure, certain infections, and certain environmental factors like exposure to benzene, cadmium, and other toxins.
People with certain blood disorders, such as monoclonal gammopathy of undetermined significance (MGUS) and light chain proteinuria, also have an increased risk of developing multiple myeloma.
In general, the risk of developing multiple myeloma increases with age and is highest in adults over the age of 60. Additionally, men are slightly more likely to be diagnosed with multiple myeloma than women.
Where does multiple myeloma usually start?
Multiple myeloma usually starts in the bone marrow. It is a form of cancer which develops in the plasma cells, which are found in the bone marrow. When it develops in the bone marrow, it crowds out the healthy plasma cells, the red blood cells, and the white blood cells, which can lead to anemia and other symptoms associated with the condition.
It can also spread to other bones, organs and tissues in the body. If a diagnosis of multiple myeloma is made, treatment options are available and may include chemotherapy, radiation, and other medications.
It’s important to speak to a doctor to explore all possible treatment options.
Can you have myeloma for years without knowing?
Yes, it is possible to have myeloma for years without knowing. Myeloma is a type of cancer that develops from white blood cells in the bone marrow, and is often undetectable during the early stages of its development.
Most symptoms associated with myeloma are vague and can be confused with other conditions, such as anemia, arthritis, or infection. In addition, many myeloma patients do not experience any symptoms during the early stages, making it difficult to detect.
As a result, myeloma is often referred to as a “silent killer” and can go undiscovered for years before it is finally diagnosed. As soon as symptoms start to appear, it is important to visit a doctor so that they can make a medical diagnosis and provide treatment, if necessary.
Can myeloma be cured if caught early?
It is possible for myeloma to be cured if it is caught early, but it is rare and generally happens only when the cancer is caught in its earliest stages. Unfortunately, if the myeloma has spread or if it is in a more advanced stage, the chances of it being cured diminish.
Treatment options such as chemotherapy and radiation can be effective in slowing the progression of the cancer and helping to keep the symptoms under control. There is also the possibility of stem cell transplants and other aspects of immunotherapy which may help put the cancer into remission.
If you are diagnosed with myeloma, it is important to consult with your doctor about the best approach for you in order to get the most out of your treatment and give yourself the best chance of achieving a cure.
What percentage of myeloma patients are high risk?
It is difficult to provide an exact percentage of myeloma patients who are considered to be high risk because different risk factors are used to evaluate an individual’s risk. Furthermore, research shows that myeloma is a heterogenous disease, meaning that no two patients present with identical disease patterns.
As a result, the risk factors and individual prognoses of each patient may vary widely.
One of the most commonly used risk stratification systems for myeloma is the International Staging System (ISS), which classifies patients into two groups: low risk and high risk. In general, between 25 and 40 percent of newly diagnosed myeloma patients are considered to be high risk when using this system.
When using other risk stratification systems, such as Durie-Salmon, Revised Millar-Sullivan, and Revised International Staging System (R-ISS), the percentage of high-risk patients can range from 30 to 70 percent.
These systems consider additional factors such as the patient’s age, the stage the disease has reached, and the levels of certain lab parameters when evaluating the individual’s risk.
In conclusion, it is difficult to provide an exact percentage of myeloma patients who are considered to be high risk, since the percentage can vary widely depending on the system of risk stratification used as well as the individual patient’s case.
Can you live 20 years with myeloma?
The answer to this question depends on a variety of factors, including the individual’s age, overall health and lifestyle habits, and the type of myeloma they have. In general, some people with myeloma can live many years with the disease and others may have a more rapid course, with survival ranging anywhere between a few months to many years.
In some cases, the type of myeloma can predict how long a person may live with the disease. For example, those with smoldering myeloma, which is typically characterized by having fewer symptoms than active myeloma, and lower levels of M protein (an immune system protein) in the blood or urine, may live longer than those with active myeloma.
Additionally, those with a more aggressive form of the disease may need more aggressive treatments, such as chemotherapy and stem cell transplants, which can result in longer survival times. And although the average age of myeloma diagnosis is around 70 years old, people of any age can be diagnosed with the disease.
That being said, those who are diagnosed at an earlier age may be more likely to live longer and may not require as aggressive treatments.
Finally, a person’s overall health and lifestyle habits may also predict how long they may live with myeloma. For example, those who are physically active, eat a balanced diet, get regular check-ups and follow their physician’s treatment instructions may live longer than those who don’t.
All in all, living 20 years with myeloma is certainly achievable for some people depending on the individual’s overall health, lifestyle habits, and type of myeloma they have.
Where does myeloma spread to first?
Myeloma is a type of cancer that affects plasma cells, which are found in the bone marrow and help to fight off infections by producing antibodies. Myeloma can spread from the bone marrow to other parts of the body, including the lymph nodes, liver, and spleen.
The first area to which myeloma will often spread is the bone, either through the bone marrow, or through direct invasion of the bone. The cancer cells can cause the bone to become weak and lead to fractures.
The bones that are most affected are typically the spine, ribs, shoulder and hip, although other areas of the body can be affected as well. Myeloma cells can also travel through the body in the bloodstream to another organs or the lymph nodes, where they can cause further damage and spread throughout the body.
It is also important to note that myeloma can spread to other organs, such as the lungs, kidney, adrenal glands, heart, or brain, but this is much less common.
What age is myeloma most common?
Myeloma is most common in older adults, with the median age of diagnosis being between 65 and 70 years old. Approximately 10% of cases are diagnosed in patients younger than 55 years old. It is relatively rare in children and is rarely seen in individuals under the age of 40.
According to the latest statistics, myeloma affected approximately 35,000 people in the US in 2019 and was responsible for over 12,000 deaths.
Does myeloma run in families?
Myeloma is a type of cancer that affects the plasma cells in the bone marrow. It is not typically considered to be hereditary, meaning it usually does not run in families. Genetic mutations are thought to play a role in the development of myeloma, but there is no clear evidence that one family member passing on the mutation increases the risk of another family member developing myeloma.
That being said, there have been some studies that suggest a possible link between myeloma and family history. These studies have reported an increased risk of myeloma in individuals with a family history of the disease, particularly among those closely related to someone with myeloma.
While these findings indicate that family history may be a factor in the development of myeloma, more research is needed to fully understand the relationship.
How common is multiple myeloma cancer by age?
Multiple myeloma is a type of cancer that usually occurs in adults over the age of 65. According to the American Cancer Society, approximately 11 out of 100,000 people aged 65 and older are diagnosed with multiple myeloma each year.
This number is equal to about 25,400 new cases of multiple myeloma per year in the United States.
The risk of multiple myeloma increases with age, and the disease is rarely found in people younger than 45. About 60% of all cases of multiple myeloma occur in people aged 65 and older. People aged 70 to 79 are the most likely to be diagnosed with multiple myeloma, followed by those aged 80 and older.
According to the American Cancer Society, men are 1.5 times more likely to develop multiple myeloma than women. African Americans are also more likely to be diagnosed with the disease than people of other racial backgrounds.
Race and sex do not play a role in determining the age a person will develop the disease.
Why is multiple myeloma on the rise?
Multiple myeloma is a type of cancer that affects the plasma cells in the body, and it is on the rise. There are a variety of theories as to why this may be the case. One potential explanation is related to an overall increase in the average age of the population; because multiple myeloma is associated with aging, older populations are more likely to develop the disorder.
Additionally, there may be environmental contributors to this rise. For example, certain chemical exposure or certain lifestyle factors (such as diet) could play a role in the development of multiple myeloma.
There may even be a genetic component, as there are certain genetic mutations that can increase the risk of multiple myeloma or other plasma cell cancers. While the reasons for the rise may not be fully understood, it is clear that something is causing this increase in incidence.
For this reason, it is important for doctors to continue to research potential causes and strive to find ways to prevent or treat this cancer.
How fast does myeloma progress?
Myeloma typically progresses slowly which is why it can often be managed effectively rather than cured. Treatment is often based on how quickly the cancer cells looks to be growing, and how much they look like other normal cells.
The average speed at which myeloma progresses can be affected by a variety of factors, such as the stage and type of myeloma, the health of the person, and their response to treatment. Generally speaking, though, it is thought that myeloma progresses slowly over a period of several years, although this progression can vary greatly from individual to individual.
There are also certain types of myeloma that can be very aggressive and progress rapidly, so the rate of progression will ultimately depend on the individual’s case. On average, approximately 30% of those diagnosed with myeloma will survive for five years or more and almost half will live for more than three years.
Therefore, the rate at which myeloma progresses depends largely on the individual, but on average it is known to progress slowly over a period of several years.